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Hes1 Is Required for Appropriate Morphogenesis and Differentiation during Mouse Thyroid Gland Development
Notch signalling plays an important role in endocrine development, through its target gene Hes1. Hes1, a bHLH transcriptional repressor, influences progenitor cell proliferation and differentiation. Recently, Hes1 was shown to be expressed in the thyroid and regulate expression of the sodium iodide...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045378/ https://www.ncbi.nlm.nih.gov/pubmed/21364918 http://dx.doi.org/10.1371/journal.pone.0016752 |