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Tumor Suppressor RASSF1A Promoter: p53 Binding and Methylation
Oncogenes and tumor suppressors work in concert to regulate cell growth or death, which is a pair of antagonist factors for regulation of tumorigenesis. Here we show promoter characteristic of tumor suppressor RASSF1A, which revealed a p53 binding site in the distal and a GC-rich region in the proxi...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045384/ https://www.ncbi.nlm.nih.gov/pubmed/21364923 http://dx.doi.org/10.1371/journal.pone.0017017 |