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Tumor Suppressor RASSF1A Promoter: p53 Binding and Methylation

Oncogenes and tumor suppressors work in concert to regulate cell growth or death, which is a pair of antagonist factors for regulation of tumorigenesis. Here we show promoter characteristic of tumor suppressor RASSF1A, which revealed a p53 binding site in the distal and a GC-rich region in the proxi...

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Detalles Bibliográficos
Autores principales: Tian, Yihao, Hou, Yu, Zhou, Xiang, Cheng, Hanhua, Zhou, Rongjia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045384/
https://www.ncbi.nlm.nih.gov/pubmed/21364923
http://dx.doi.org/10.1371/journal.pone.0017017