Insights into the Function of the CRM1 Cofactor RanBP3 from the Structure of Its Ran-Binding Domain

Proteins bearing a leucine-rich nuclear export signal (NES) are exported from the nucleus by the transport factor CRM1, which forms a cooperative ternary complex with the NES-bearing cargo and with the small GTPase Ran. CRM1-mediated export is regulated by RanBP3, a Ran-interacting nuclear protein....

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Detalles Bibliográficos
Autores principales: Langer, Karla, Dian, Cyril, Rybin, Vladimir, Müller, Christoph W., Petosa, Carlo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045386/
https://www.ncbi.nlm.nih.gov/pubmed/21364925
http://dx.doi.org/10.1371/journal.pone.0017011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045386/
https://www.ncbi.nlm.nih.gov/pubmed/21364925
http://dx.doi.org/10.1371/journal.pone.0017011

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