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Insights into the Function of the CRM1 Cofactor RanBP3 from the Structure of Its Ran-Binding Domain
Proteins bearing a leucine-rich nuclear export signal (NES) are exported from the nucleus by the transport factor CRM1, which forms a cooperative ternary complex with the NES-bearing cargo and with the small GTPase Ran. CRM1-mediated export is regulated by RanBP3, a Ran-interacting nuclear protein....
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045386/ https://www.ncbi.nlm.nih.gov/pubmed/21364925 http://dx.doi.org/10.1371/journal.pone.0017011 |