A single-tube allele specific-polymerase chain reaction to detect T315I resistant mutation in chronic myeloid leukemia patients

BACKGROUND: BCR-ABL kinase domain (KD) mutation is the major mechanism contributing to suboptimal response to tyrosine kinase inhibitors (TKI) in BCR-ABL-positive chronic myeloid leukemia (CML) patients. T315I mutation, as one of the most frequent KD mutations, has been shown to be strongly associat...

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Detalles Bibliográficos
Autores principales: Wongboonma, Wanwisa, Thongnoppakhun, Wanna, Auewarakul, Chirayu U
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045387/
https://www.ncbi.nlm.nih.gov/pubmed/21303525
http://dx.doi.org/10.1186/1756-8722-4-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045387/
https://www.ncbi.nlm.nih.gov/pubmed/21303525
http://dx.doi.org/10.1186/1756-8722-4-7

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