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TLR3 and TLR7 Modulate IgE Production in Antigen Induced Pulmonary Inflammation via Influencing IL-4 Expression in Immune Organs

BACKGROUND: Toll-like receptors (TLRs) as pattern recognition receptors, participate in both innate and adaptive immune responses, and seem to play an important role in the pathogenesis of asthma. This study aimed to identify key TLRs involved in antigen induced pulmonary inflammation (AIPI), a rat...

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Detalles Bibliográficos
Autores principales: Meng, Liesu, He, Xiaojing, Zhu, Wenhua, Yang, Xudong, Jiang, Congshan, Sun, Qingzhu, Raza M.B., Asim, Zhang, Simeng, Xue, Qian, Xie, Xinfang, Lu, Shemin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045401/
https://www.ncbi.nlm.nih.gov/pubmed/21364926
http://dx.doi.org/10.1371/journal.pone.0017252