Apoptosis Induced by Cytoskeletal Disruption Requires Distinct Domains of MEKK1

MEKK1 is a mitogen-activated protein kinase kinase kinase (MAP3K) that activates the MAPK JNK and is required for microtubule inhibitor-induced apoptosis in B cells. Here, we find that apoptosis induced by actin disruption via cytochalasin D and by the protein phosphatase 1/2A inhibitor okadaic acid...

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Detalles Bibliográficos
Autores principales: Tricker, Erin, Arvand, Afsane, Kwan, Raymond, Chen, Gordon Y., Gallagher, Ewen, Cheng, Genhong
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045432/
https://www.ncbi.nlm.nih.gov/pubmed/21364884
http://dx.doi.org/10.1371/journal.pone.0017310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045432/
https://www.ncbi.nlm.nih.gov/pubmed/21364884
http://dx.doi.org/10.1371/journal.pone.0017310

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