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Apoptosis Induced by Cytoskeletal Disruption Requires Distinct Domains of MEKK1
MEKK1 is a mitogen-activated protein kinase kinase kinase (MAP3K) that activates the MAPK JNK and is required for microtubule inhibitor-induced apoptosis in B cells. Here, we find that apoptosis induced by actin disruption via cytochalasin D and by the protein phosphatase 1/2A inhibitor okadaic acid...
Autores principales: | Tricker, Erin, Arvand, Afsane, Kwan, Raymond, Chen, Gordon Y., Gallagher, Ewen, Cheng, Genhong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045432/ https://www.ncbi.nlm.nih.gov/pubmed/21364884 http://dx.doi.org/10.1371/journal.pone.0017310 |
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