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Starvation Induced Cell Death in Autophagy-Defective Yeast Mutants Is Caused by Mitochondria Dysfunction

Autophagy is a highly-conserved cellular degradation and recycling system that is essential for cell survival during nutrient starvation. The loss of viability had been used as an initial screen to identify autophagy-defective (atg) mutants of the yeast Saccharomyces cerevisiae, but the mechanism of...

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Detalles Bibliográficos
Autores principales: Suzuki, Sho W., Onodera, Jun, Ohsumi, Yoshinori
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045454/
https://www.ncbi.nlm.nih.gov/pubmed/21364763
http://dx.doi.org/10.1371/journal.pone.0017412