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The Roles of Transmembrane Domain Helix-III during Rhodopsin Photoactivation
BACKGROUND: Rhodopsin, the prototypic member of G protein-coupled receptors (GPCRs), undergoes isomerization of 11-cis-retinal to all-trans-retinal upon photoactivation. Although the basic mechanism by which rhodopsin is activated is well understood, the roles of whole transmembrane (TM) helix-III d...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045455/ https://www.ncbi.nlm.nih.gov/pubmed/21364764 http://dx.doi.org/10.1371/journal.pone.0017398 |