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Upstream open reading frames: Molecular switches in (patho)physiology

Conserved upstream open reading frames (uORFs) are found within many eukaryotic transcripts and are known to regulate protein translation. Evidence from genetic and bioinformatic studies implicates disturbed uORF-mediated translational control in the etiology of human diseases. A genetic mouse model...

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Detalles Bibliográficos
Autores principales: Wethmar, Klaus, Smink, Jeske J, Leutz, Achim
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045505/
https://www.ncbi.nlm.nih.gov/pubmed/20726009
http://dx.doi.org/10.1002/bies.201000037