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A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs

Chromatin immunoprecipitation (ChIP) followed by high throughput sequencing (ChIP-seq) is rapidly becoming the method of choice for discovering cell-specific transcription factor binding locations genome wide. By aligning sequenced tags to the genome, binding locations appear as peaks in the tag pro...

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Detalles Bibliográficos
Autores principales: Rye, Morten Beck, Sætrom, Pål, Drabløs, Finn
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045577/
https://www.ncbi.nlm.nih.gov/pubmed/21113027
http://dx.doi.org/10.1093/nar/gkq1187