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A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs
Chromatin immunoprecipitation (ChIP) followed by high throughput sequencing (ChIP-seq) is rapidly becoming the method of choice for discovering cell-specific transcription factor binding locations genome wide. By aligning sequenced tags to the genome, binding locations appear as peaks in the tag pro...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045577/ https://www.ncbi.nlm.nih.gov/pubmed/21113027 http://dx.doi.org/10.1093/nar/gkq1187 |