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Hpy188I–DNA pre- and post-cleavage complexes—snapshots of the GIY-YIG nuclease mediated catalysis

The GIY-YIG nuclease domain is present in all kingdoms of life and has diverse functions. It is found in the eukaryotic flap endonuclease and Holliday junction resolvase Slx1–Slx4, the prokaryotic nucleotide excision repair proteins UvrC and Cho, and in proteins of ‘selfish’ genetic elements. Here w...

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Detalles Bibliográficos
Autores principales: Sokolowska, Monika, Czapinska, Honorata, Bochtler, Matthias
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045582/
https://www.ncbi.nlm.nih.gov/pubmed/20935048
http://dx.doi.org/10.1093/nar/gkq821