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Verification of alternative splicing variants based on domain integrity, truncation length and intrinsic protein disorder
According to current estimations ∼95% of multi-exonic human protein-coding genes undergo alternative splicing (AS). However, for 4000 human proteins in PDB, only 14 human proteins have structures of at least two alternative isoforms. Surveying these structural isoforms revealed that the maximum inse...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045584/ https://www.ncbi.nlm.nih.gov/pubmed/20972208 http://dx.doi.org/10.1093/nar/gkq843 |