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Co-transcriptional RNA cleavage provides a failsafe termination mechanism for yeast RNA polymerase I

Ribosomal RNA, transcribed by RNA polymerase (Pol) I, accounts for most cellular RNA. Since Pol I transcribes rDNA repeats with high processivity and polymerase density, transcription termination is a critical process. Early in vitro studies proposed polymerase pausing by Reb1 and transcript release...

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Detalles Bibliográficos
Autores principales: Braglia, Priscilla, Kawauchi, Junya, Proudfoot, Nick J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045592/
https://www.ncbi.nlm.nih.gov/pubmed/20972219
http://dx.doi.org/10.1093/nar/gkq894