Probing the in vitro mechanism of action of cationic lipid/DNA lipoplexes at a nanometric scale

Cationic lipids are used for delivering nucleic acids (lipoplexes) into cells for both therapeutic and biological applications. A better understanding of the identified key-steps, including endocytosis, endosomal escape and nuclear delivery is required for further developments to improve their effic...

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Detalles Bibliográficos
Autores principales: Le Bihan, Olivier, Chèvre, Raphaël, Mornet, Stéphane, Garnier, Boris, Pitard, Bruno, Lambert, Olivier
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Synthetic Biology and Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045597/
https://www.ncbi.nlm.nih.gov/pubmed/21078679
http://dx.doi.org/10.1093/nar/gkq921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045597/
https://www.ncbi.nlm.nih.gov/pubmed/21078679
http://dx.doi.org/10.1093/nar/gkq921

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