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Probing the in vitro mechanism of action of cationic lipid/DNA lipoplexes at a nanometric scale
Cationic lipids are used for delivering nucleic acids (lipoplexes) into cells for both therapeutic and biological applications. A better understanding of the identified key-steps, including endocytosis, endosomal escape and nuclear delivery is required for further developments to improve their effic...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045597/ https://www.ncbi.nlm.nih.gov/pubmed/21078679 http://dx.doi.org/10.1093/nar/gkq921 |