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Assembly of a fragmented ribonucleotide reductase by protein interaction domains derived from a mobile genetic element

Ribonucleotide reductase (RNR) is a critical enzyme of nucleotide metabolism, synthesizing precursors for DNA replication and repair. In prokaryotic genomes, RNR genes are commonly targeted by mobile genetic elements, including free standing and intron-encoded homing endonucleases and inteins. Here,...

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Detalles Bibliográficos
Autores principales: Crona, Mikael, Moffatt, Connor, Friedrich, Nancy C., Hofer, Anders, Sjöberg, Britt-Marie, Edgell, David R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045599/
https://www.ncbi.nlm.nih.gov/pubmed/20972217
http://dx.doi.org/10.1093/nar/gkq924