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Quantifying the energetic contributions of desolvation and π-electron density during translesion DNA synthesis
This report examines the molecular mechanism by which high-fidelity DNA polymerases select nucleotides during the replication of an abasic site, a non-instructional DNA lesion. This was accomplished by synthesizing several unique 5-substituted indolyl 2′-deoxyribose triphosphates and defining their...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045600/ https://www.ncbi.nlm.nih.gov/pubmed/20952399 http://dx.doi.org/10.1093/nar/gkq925 |