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Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer

The HMG-domain transcription factor Sox10 is expressed throughout oligodendrocyte development and is an important component of the transcriptional regulatory network in these myelin-forming CNS glia. Of the known Sox10 regulatory regions, only the evolutionary conserved U2 enhancer in the distal 5′-...

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Detalles Bibliográficos
Autores principales: Küspert, Melanie, Hammer, Alexander, Bösl, Michael R., Wegner, Michael
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045606/
https://www.ncbi.nlm.nih.gov/pubmed/20959288
http://dx.doi.org/10.1093/nar/gkq951