Bach1 gene ablation reduces steatohepatitis in mouse MCD diet model

Bach1 is a transcriptional repressor of heme oxygenase-1 (HO-1, a.k.a. HSP-32), which is an inducible enzyme and has anti-oxidation/anti-inflammatory properties shown in various models of organ injuries. Since oxidative stress plays a pivotal role in the pathogenesis of nonalcoholic steatohepatitis...

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Detalles Bibliográficos
Autores principales: Inoue, Motoki, Tazuma, Susumu, Kanno, Keishi, Hyogo, Hideyuki, Igarashi, Kazuhiko, Chayama, Kazuaki
Formato: Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045690/
https://www.ncbi.nlm.nih.gov/pubmed/21373270
http://dx.doi.org/10.3164/jcbn.09-122GFR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045690/
https://www.ncbi.nlm.nih.gov/pubmed/21373270
http://dx.doi.org/10.3164/jcbn.09-122GFR

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