RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion

BACKGROUND: The thymus is a central lymphoid organ, in which bone marrow-derived T cell precursors undergo a complex process of maturation. Developing thymocytes interact with thymic microenvironment in a defined spatial order. A component of thymic microenvironment, the thymic epithelial cells, is...

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Detalles Bibliográficos
Autores principales: Linhares-Lacerda, Leandra, Ribeiro-Alves, Marcelo, Nogueira, Ana Cristina Martins de Almeida, Mendes-da-Cruz, Daniella Areas, Magalhães, Danielle Aparecida, Dardenne, Mireille, Passos, Geraldo Aleixo, Savino, Wilson
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045795/
https://www.ncbi.nlm.nih.gov/pubmed/21210968
http://dx.doi.org/10.1186/1471-2164-11-S5-S2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045795/
https://www.ncbi.nlm.nih.gov/pubmed/21210968
http://dx.doi.org/10.1186/1471-2164-11-S5-S2

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