Cargando…

RNA interference-mediated knockdown of CD49e (α5 integrin chain) in human thymic epithelial cells modulates the expression of multiple genes and decreases thymocyte adhesion

BACKGROUND: The thymus is a central lymphoid organ, in which bone marrow-derived T cell precursors undergo a complex process of maturation. Developing thymocytes interact with thymic microenvironment in a defined spatial order. A component of thymic microenvironment, the thymic epithelial cells, is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Linhares-Lacerda, Leandra, Ribeiro-Alves, Marcelo, Nogueira, Ana Cristina Martins de Almeida, Mendes-da-Cruz, Daniella Areas, Magalhães, Danielle Aparecida, Dardenne, Mireille, Passos, Geraldo Aleixo, Savino, Wilson
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045795/ https://www.ncbi.nlm.nih.gov/pubmed/21210968 http://dx.doi.org/10.1186/1471-2164-11-S5-S2

Ejemplares similares

Editorial: The Role of Aire, microRNAs and Cell–Cell Interactions on Thymic Architecture and Induction of Tolerance
por: Passos, Geraldo Aleixo, et al.
Publicado: (2015)

The Thymic Orchestration Involving Aire, miRNAs, and Cell–Cell Interactions during the Induction of Central Tolerance
por: Passos, Geraldo Aleixo, et al.
Publicado: (2015)

Role of β2 Integrins in the Binding of Thymocytes to Rat Thymic Macrophages
por: Čolić, Miodrag, et al.
Publicado: (1994)

A novel integrin involved in thymocyte-thymic epithelial cell interactions
Publicado: (1991)

Laminin-Mediated Interactions in Thymocyte Migration and Development
por: Savino, Wilson, et al.
Publicado: (2015)

Differential Expression of microRNAs in Thymic Epithelial Cells from Trypanosoma cruzi Acutely Infected Mice: Putative Role in Thymic Atrophy
por: Linhares-Lacerda, Leandra, et al.
Publicado: (2015)

Aire Disruption Influences the Medullary Thymic Epithelial Cell Transcriptome and Interaction With Thymocytes
por: Speck-Hernandez, Cesar A., et al.
Publicado: (2018)

Sphingosine-1-Phosphate Receptor 1 Is Involved in Non-Obese Diabetic Mouse Thymocyte Migration Disorders
por: Lemos, Julia P., et al.
Publicado: (2018)

Thymic exosomes promote the final maturation of thymocytes
por: Lundberg, Vanja, et al.
Publicado: (2016)

Fibronectin modulates thymocyte-thymic epithelial cell interactions following Trypanosoma cruzi infection
por: Farias-de-Oliveira, Désio Aurélio, et al.
Publicado: (2013)

Effects of sex steroids on thymic epithelium and thymocyte development
por: Taves, Matthew D., et al.
Publicado: (2022)

Mechanisms Involved in the Binding of Thymocytes to Rat Thymic Dendritic Cells
por: Čolić, Miodrag, et al.
Publicado: (1996)

Intercellular Protein Transfer from Thymocytes to Thymic Epithelial Cells
por: Wang, Hong-Xia, et al.
Publicado: (2016)

An anti-DEC-205 monoclonal antibody stimulates binding of thymocytes to rat thymic dendritic cells and promotes apoptosis of thymocytes
por: Majstorović, Ivana, et al.
Publicado: (2014)

Bidirectional Interactions Between Thymocytes and Thymic Epithelial Cell Lines in Vitro
por: Čolić, Miodrag, et al.
Publicado: (1998)

Thymic Microenvironment: Interactions Between Innate Immune Cells and Developing Thymocytes
por: Wang, Helen, et al.
Publicado: (2022)

In vitro maturation of immature thymocytes into immunocompetent T cells in the absence of direct thymic influence
por: Irle, C, et al.
Publicado: (1978)

Antigen Recognition By Autoreactive Cd4(+) Thymocytes Drives Homeostasis Of The Thymic Medulla
por: Irla, Magali, et al.
Publicado: (2012)

Maturation and migration of murine CD4 single positive thymocytes and thymic emigrants
por: Xu, Xi, et al.
Publicado: (2014)

Inhibins Tune the Thymocyte Selection Process by Regulating Thymic Stromal Cell Differentiation
por: Carbajal-Franco, Ebzadrel, et al.
Publicado: (2015)

How Many Thymic Epithelial Cells Are Necessary for a Proper Maturation of Thymocytes?
por: Montero-Herradón, Sara, et al.
Publicado: (2021)

Role of Small RNAs in Trypanosomatid Infections
por: Linhares-Lacerda, Leandra, et al.
Publicado: (2016)

Different Subpopulations of Developing Thymocytes are Associated with Adherent (Macrophage) or Nonadherent (Dendritic) Thymic Rosettes
por: Shortman, Ken, et al.
Publicado: (1991)

Seeding of thymic microenvironments defined by distinct thymocyte- stromal cell interactions is developmentally controlled
Publicado: (1987)

Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression
por: Lustig, Ana, et al.
Publicado: (2009)

The thymic medulla is required for Foxp3(+) regulatory but not conventional CD4(+) thymocyte development
por: Cowan, Jennifer E., et al.
Publicado: (2013)

Thymic tuft cells promote an IL4-enriched medulla and shape thymocyte development
por: Miller, Corey N., et al.
Publicado: (2018)

E-protein–regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex
por: Kadakia, Tejas, et al.
Publicado: (2019)

Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire(−/−) mice
por: Jin, Rong, et al.
Publicado: (2016)

Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
por: Lopes, Noella, et al.
Publicado: (2022)

Thymic Microenvironment Is Modified by Malnutrition and Leishmania infantum Infection
por: Losada-Barragán, Monica, et al.
Publicado: (2019)

miR-155 exerts posttranscriptional control of autoimmune regulator (Aire) and tissue-restricted antigen genes in medullary thymic epithelial cells
por: Tanaka, Pedro Paranhos, et al.
Publicado: (2022)

Human Thymic Epithelial Cells in Serum-Free Culture: Nature and Effects on Thymocyte Cell Lines
por: Ropke, Carsten, et al.
Publicado: (1992)

Differentiation of CD3-4-8- thymocytes in short-term thymic stromal cell culture
Publicado: (1992)

Galectin-1, an Endogenous Lectin Produced by Thymic Epithelial Cells, Induces Apoptosis of Human Thymocytes
por: Perillo, Nancy L., et al.
Publicado: (1997)

Thymic Atrophy and Apoptosis of CD4(+)CD8(+) Thymocytes in the Cuprizone Model of Multiple Sclerosis
por: Solti, Izabella, et al.
Publicado: (2015)

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress
por: Malcolm, Tim I. M., et al.
Publicado: (2016)

Growth hormone in the presence of laminin modulates interaction of human thymic epithelial cells and thymocytes in vitro
por: Lins, Marvin Paulo, et al.
Publicado: (2016)

CCR2 Signal Facilitates Thymic Egress by Priming Thymocyte Responses to Sphingosine-1-Phosphate
por: Aili, Abudureyimujiang, et al.
Publicado: (2018)

Thymic DCs derived IL-27 regulates the final maturation of CD4(+) SP thymocytes
por: Tang, Hui, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_da1ijq9j5ltdc459ht7jtlhtoq