Mining flexible-receptor docking experiments to select promising protein receptor snapshots

BACKGROUND: Molecular docking simulation is the Rational Drug Design (RDD) step that investigates the affinity between protein receptors and ligands. Typically, molecular docking algorithms consider receptors as rigid bodies. Receptors are, however, intrinsically flexible in the cellular environment...

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Detalles Bibliográficos
Autores principales: Machado, Karina S, Winck, Ana T, Ruiz, Duncan DA, Norberto de Souza, Osmar
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045799/
https://www.ncbi.nlm.nih.gov/pubmed/21210972
http://dx.doi.org/10.1186/1471-2164-11-S5-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045799/
https://www.ncbi.nlm.nih.gov/pubmed/21210972
http://dx.doi.org/10.1186/1471-2164-11-S5-S6

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