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Mining flexible-receptor docking experiments to select promising protein receptor snapshots
BACKGROUND: Molecular docking simulation is the Rational Drug Design (RDD) step that investigates the affinity between protein receptors and ligands. Typically, molecular docking algorithms consider receptors as rigid bodies. Receptors are, however, intrinsically flexible in the cellular environment...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045799/ https://www.ncbi.nlm.nih.gov/pubmed/21210972 http://dx.doi.org/10.1186/1471-2164-11-S5-S6 |