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A machine learning approach for genome-wide prediction of morbid and druggable human genes based on systems-level data

BACKGROUND: The genome-wide identification of both morbid genes, i.e., those genes whose mutations cause hereditary human diseases, and druggable genes, i.e., genes coding for proteins whose modulation by small molecules elicits phenotypic effects, requires experimental approaches that are time-cons...

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Detalles Bibliográficos
Autores principales: Costa, Pedro R, Acencio, Marcio L, Lemke, Ney
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045802/
https://www.ncbi.nlm.nih.gov/pubmed/21210975
http://dx.doi.org/10.1186/1471-2164-11-S5-S9