Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs

Long interspersed elements, type 1(LINE-1, L1) are the most abundant and only active autonomous retrotransposons in the human genome. Native L1 elements are inefficiently expressed because of a transcription elongation defect thought to be caused by high adenosine content in L1 sequences. Previously...

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Detalles Bibliográficos
Autores principales: An, Wenfeng, Dai, Lixin, Niewiadomska, Anna Maria, Yetil, Alper, O'Donnell, Kathryn A, Han, Jeffrey S, Boeke, Jef D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045867/
https://www.ncbi.nlm.nih.gov/pubmed/21320307
http://dx.doi.org/10.1186/1759-8753-2-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045867/
https://www.ncbi.nlm.nih.gov/pubmed/21320307
http://dx.doi.org/10.1186/1759-8753-2-2

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