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Enzymatic analysis of the effect of naturally occurring Leu138Pro mutation identified in SHV β-lactamase on hydrolysis of penicillin and ampicillin
BACKGROUND: The aim of this study was to analyze the significance of leucine to proline substitution at position 138(Leu138Pro) on the hydrolysis of penicillin and ampicillin that we identified in the bla(SHV )gene of clinical Escherichia coli swine isolate. RESULTS: Kinetic analysis of the mutant p...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045869/ https://www.ncbi.nlm.nih.gov/pubmed/21291571 http://dx.doi.org/10.1186/1471-2180-11-29 |