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Expression and shedding of endothelial protein C receptor in prostate cancer cells

BACKGROUND: Increasing evidences show that beyond its role in coagulation, endothelial protein C receptor (EPCR) interferes with carcinogenesis. Pro-carcinogenic effects of EPCR were linked with a raised generation of activated protein C (aPC) and anti-apoptotic signalling. This study was carried ou...

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Detalles Bibliográficos
Autores principales: Menschikowski, Mario, Hagelgans, Albert, Tiebel, Oliver, Klinsmann, Ludwig, Eisenhofer, Graeme, Siegert, Gabriele
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045874/
https://www.ncbi.nlm.nih.gov/pubmed/21320357
http://dx.doi.org/10.1186/1475-2867-11-4