Systematic search for enhancer elements and somatic allelic imbalance at seven low-penetrance colorectal cancer predisposition loci

BACKGROUND: Common single-nucleotide polymorphisms (SNPs) in ten chromosomal loci have been shown to predispose to colorectal cancer (CRC) in genome-wide association studies. A plausible biological mechanism of CRC susceptibility associated with genetic variation has so far only been proposed for th...

Descripción completa

Detalles Bibliográficos
Autores principales: Niittymäki, Iina, Tuupanen, Sari, Li, Yilong, Järvinen, Heikki, Mecklin, Jukka-Pekka, Tomlinson, Ian PM, Houlston, Richard S, Karhu, Auli, Aaltonen, Lauri A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045878/
https://www.ncbi.nlm.nih.gov/pubmed/21314996
http://dx.doi.org/10.1186/1471-2350-12-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045878/
https://www.ncbi.nlm.nih.gov/pubmed/21314996
http://dx.doi.org/10.1186/1471-2350-12-23

Ejemplares similares