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Identification of errors introduced during high throughput sequencing of the T cell receptor repertoire
BACKGROUND: Recent advances in massively parallel sequencing have increased the depth at which T cell receptor (TCR) repertoires can be probed by >3log10, allowing for saturation sequencing of immune repertoires. The resolution of this sequencing is dependent on its accuracy, and direct assessmen...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045962/ https://www.ncbi.nlm.nih.gov/pubmed/21310087 http://dx.doi.org/10.1186/1471-2164-12-106 |