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Importin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzyme

SUMOylation, reversible attachment of small ubiquitin-related modifier (SUMO), serves to regulate hundreds of proteins. Consistent with predominantly nuclear targets, enzymes required for attachment and removal of SUMO are highly enriched in this compartment. This is true also for the first enzyme o...

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Detalles Bibliográficos
Autores principales: Moutty, Marie Christine, Sakin, Volkan, Melchior, Frauke
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046061/
https://www.ncbi.nlm.nih.gov/pubmed/21209321
http://dx.doi.org/10.1091/mbc.E10-05-0461