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Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK

During mitosis, the nuclear pore complex is disassembled and, increasingly, nucleoporins are proving to have mitotic functions when released from the pore. We find a contribution of the nucleoporin Nup98 to mitotic spindle assembly through regulation of microtubule dynamics. When added to Xenopus ex...

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Detalles Bibliográficos
Autores principales: Cross, Marie K., Powers, Maureen A.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046062/
https://www.ncbi.nlm.nih.gov/pubmed/21209315
http://dx.doi.org/10.1091/mbc.E10-06-0478