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Mouse models and the interpretation of human GWAS in type 2 diabetes and obesity
Within the last 3 years, genome-wide association studies (GWAS) have had unprecedented success in identifying loci that are involved in common diseases. For example, more than 35 susceptibility loci have been identified for type 2 diabetes and 32 for obesity thus far. However, the causal gene and va...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046087/ https://www.ncbi.nlm.nih.gov/pubmed/21324932 http://dx.doi.org/10.1242/dmm.000414 |