A mouse model for monitoring islet cell genesis and developing therapies for diabetes

Transient expression of the transcription factor neurogenin-3 marks progenitor cells in the pancreas as they differentiate into islet cells. We developed a transgenic mouse line in which the surrogate markers secreted alkaline phosphatase (SeAP) and enhanced green florescent protein (EGFP) can be us...

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Detalles Bibliográficos
Autores principales: Shimajiri, Yoshinori, Kosaka, Yasuhiro, Scheel, David W., Lynn, Francis C., Kishimoto, Nina, Wang, Juehu, Zhao, Shuhong, German, Michael S.
Formato: Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2011
Materias:
Resource Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046103/
https://www.ncbi.nlm.nih.gov/pubmed/21135059
http://dx.doi.org/10.1242/dmm.002998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046103/
https://www.ncbi.nlm.nih.gov/pubmed/21135059
http://dx.doi.org/10.1242/dmm.002998

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