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Systematic Two-Hybrid and Comparative Proteomic Analyses Reveal Novel Yeast Pre-mRNA Splicing Factors Connected to Prp19

Prp19 is the founding member of the NineTeen Complex, or NTC, which is a spliceosomal subcomplex essential for spliceosome activation. To define Prp19 connectivity and dynamic protein interactions within the spliceosome, we systematically queried the Saccharomyces cerevisiae proteome for Prp19 WD40...

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Detalles Bibliográficos
Autores principales: Ren, Liping, McLean, Janel R., Hazbun, Tony R., Fields, Stanley, Vander Kooi, Craig, Ohi, Melanie D., Gould, Kathleen L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046128/
https://www.ncbi.nlm.nih.gov/pubmed/21386897
http://dx.doi.org/10.1371/journal.pone.0016719