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2-Deoxy-D-Glucose Treatment of Endothelial Cells Induces Autophagy by Reactive Oxygen Species-Mediated Activation of the AMP-Activated Protein Kinase

Autophagy is a cellular self-digestion process activated in response to stresses such as energy deprivation and oxidative stress. However, the mechanisms by which energy deprivation and oxidative stress trigger autophagy remain undefined. Here, we report that activation of AMP-activated protein kina...

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Detalles Bibliográficos
Autores principales: Wang, Qilong, Liang, Bin, Shirwany, Najeeb A., Zou, Ming-Hui
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046135/
https://www.ncbi.nlm.nih.gov/pubmed/21386904
http://dx.doi.org/10.1371/journal.pone.0017234