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A Rapid Flp-In System for Expression of Secreted H5N1 Influenza Hemagglutinin Vaccine Immunogen in Mammalian Cells

BACKGROUND: Continuing transmissions of highly pathogenic H5N1 viruses in poultry and humans underscores the need for a rapid response to potential pandemic in the form of vaccine. Recombinant technologies for production of immunogenic hemagglutinin (HA) could provide an advantage over the tradition...

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Detalles Bibliográficos
Autores principales: Lu, Hanxin, Khurana, Surender, Verma, Nitin, Manischewitz, Jody, King, Lisa, Beigel, John H., Golding, Hana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046144/
https://www.ncbi.nlm.nih.gov/pubmed/21386997
http://dx.doi.org/10.1371/journal.pone.0017297