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Nod2 Suppresses Borrelia burgdorferi Mediated Murine Lyme Arthritis and Carditis through the Induction of Tolerance

The internalization of Borrelia burgdorferi, the causative agent of Lyme disease, by phagocytes is essential for an effective activation of the immune response to this pathogen. The intracellular, cytosolic receptor Nod2 has been shown to play varying roles in either enhancing or attenuating inflamm...

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Detalles Bibliográficos
Autores principales: Petnicki-Ocwieja, Tanja, DeFrancesco, Alicia S., Chung, Erin, Darcy, Courtney T., Bronson, Roderick T., Kobayashi, Koichi S., Hu, Linden T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046161/
https://www.ncbi.nlm.nih.gov/pubmed/21387014
http://dx.doi.org/10.1371/journal.pone.0017414