Practical and Theoretical Considerations in Study Design for Detecting Gene-Gene Interactions Using MDR and GMDR Approaches

Detection of interacting risk factors for complex traits is challenging. The choice of an appropriate method, sample size, and allocation of cases and controls are serious concerns. To provide empirical guidelines for planning such studies and data analyses, we investigated the performance of the mu...

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Detalles Bibliográficos
Autores principales: Chen, Guo-Bo, Xu, Yi, Xu, Hai-Ming, Li, Ming D., Zhu, Jun, Lou, Xiang-Yang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046176/
https://www.ncbi.nlm.nih.gov/pubmed/21386969
http://dx.doi.org/10.1371/journal.pone.0016981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046176/
https://www.ncbi.nlm.nih.gov/pubmed/21386969
http://dx.doi.org/10.1371/journal.pone.0016981

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