Cytoplasmic Skp2 Expression Is Increased in Human Melanoma and Correlated with Patient Survival

BACKGROUND: S-phase kinase protein 2 (Skp2), an F-box protein, targets cell cycle regulators via ubiquitin-mediated degradation. Skp2 is frequently overexpressed in a variety of cancers and associated with patient survival. In melanoma, however, the prognostic significance of subcellular Skp2 expres...

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Detalles Bibliográficos
Autores principales: Chen, Guangdi, Cheng, Yabin, Zhang, Zhizhong, Martinka, Magdalena, Li, Gang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046256/
https://www.ncbi.nlm.nih.gov/pubmed/21386910
http://dx.doi.org/10.1371/journal.pone.0017578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046256/
https://www.ncbi.nlm.nih.gov/pubmed/21386910
http://dx.doi.org/10.1371/journal.pone.0017578

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