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Expression of the stem cell marker ALDH1 in BRCA1 related breast cancer

INTRODUCTION: The BRCA1 protein makes mammary stem cells differentiate into mature luminal and myoepithelial cells. If a BRCA1 mutation results in a differentiation block, an enlarged stem cell component might be present in the benign tissue of BRCA1 mutation carriers, and these mammary stem cells c...

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Detalles Bibliográficos
Autores principales: Heerma van Voss, Marise R., van der Groep, Petra, Bart, Joost, van der Wall, Elsken, van Diest, Paul J.
Formato: Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046359/
https://www.ncbi.nlm.nih.gov/pubmed/21336637
http://dx.doi.org/10.1007/s13402-010-0007-3