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Expression of the stem cell marker ALDH1 in BRCA1 related breast cancer
INTRODUCTION: The BRCA1 protein makes mammary stem cells differentiate into mature luminal and myoepithelial cells. If a BRCA1 mutation results in a differentiation block, an enlarged stem cell component might be present in the benign tissue of BRCA1 mutation carriers, and these mammary stem cells c...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046359/ https://www.ncbi.nlm.nih.gov/pubmed/21336637 http://dx.doi.org/10.1007/s13402-010-0007-3 |