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Divergent transcriptional activities determine limb identity

Limbs develop using a common genetic programme despite widely differing morphologies. This programme is modulated by limb-restricted regulators such as hindlimb (HL) transcription factors Pitx1 and Tbx4 and the forelimb (FL) Tbx5. Both Tbx factors have been implicated in limb patterning and growth,...

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Detalles Bibliográficos
Autores principales: Ouimette, Jean-François, Jolin, Marisol Lavertu, L'honoré, Aurore, Gifuni, Anthony, Drouin, Jacques
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046407/
https://www.ncbi.nlm.nih.gov/pubmed/20975709
http://dx.doi.org/10.1038/ncomms1036