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Activity map of the tammar X chromosome shows that marsupial X inactivation is incomplete and escape is stochastic

BACKGROUND: X chromosome inactivation is a spectacular example of epigenetic silencing. In order to deduce how this complex system evolved, we examined X inactivation in a model marsupial, the tammar wallaby (Macropus eugenii). In marsupials, X inactivation is known to be paternal, incomplete and ti...

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Detalles Bibliográficos
Autores principales: Al Nadaf, Shafagh, Waters, Paul D, Koina, Edda, Deakin, Janine E, Jordan, Kristen S, Graves, Jennifer AM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046482/
https://www.ncbi.nlm.nih.gov/pubmed/21182760
http://dx.doi.org/10.1186/gb-2010-11-12-r122