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Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits

INTRODUCTION: Synovial mesenchymal stem cells (MSCs) have high proliferative and chondrogenic potentials, and MSCs transplanted into the articular cartilage defect produce abundant extracellular matrix. Because of similarities between the articular cartilage and the intervertebral disc cartilage, sy...

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Detalles Bibliográficos
Autores principales: Miyamoto, Takashi, Muneta, Takeshi, Tabuchi, Takashi, Matsumoto, Kenji, Saito, Hirohisa, Tsuji, Kunikazu, Sekiya, Ichiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046513/
https://www.ncbi.nlm.nih.gov/pubmed/21054867
http://dx.doi.org/10.1186/ar3182