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Intradiscal transplantation of synovial mesenchymal stem cells prevents intervertebral disc degeneration through suppression of matrix metalloproteinase-related genes in nucleus pulposus cells in rabbits
INTRODUCTION: Synovial mesenchymal stem cells (MSCs) have high proliferative and chondrogenic potentials, and MSCs transplanted into the articular cartilage defect produce abundant extracellular matrix. Because of similarities between the articular cartilage and the intervertebral disc cartilage, sy...
Autores principales: | Miyamoto, Takashi, Muneta, Takeshi, Tabuchi, Takashi, Matsumoto, Kenji, Saito, Hirohisa, Tsuji, Kunikazu, Sekiya, Ichiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046513/ https://www.ncbi.nlm.nih.gov/pubmed/21054867 http://dx.doi.org/10.1186/ar3182 |
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