Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model

INTRODUCTION: Rheumatoid arthritis is an autoimmune disease in which joint inflammation leads to progressive cartilage and bone erosion. Matrix metalloproteinases (MMPs) implicated in homeostasis of the extracellular matrix play a central role in cartilage degradation. However, the role of specific...

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Detalles Bibliográficos
Autores principales: García, Samuel, Forteza, Jerónimo, López-Otin, Carlos, Gómez-Reino, Juan J, González, Antonio, Conde, Carmen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046537/
https://www.ncbi.nlm.nih.gov/pubmed/21190566
http://dx.doi.org/10.1186/ar3211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046537/
https://www.ncbi.nlm.nih.gov/pubmed/21190566
http://dx.doi.org/10.1186/ar3211

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