RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1

INTRODUCTION: Regulatory factor X-box 1 (RFX1) can interact with DNA methyltransferase 1 (DNMT1) and histone deacetylase 1 (HDAC1), and RFX1 down-regulation contributes to DNA hypomethylation and histone H3 hyperacetylation at the cluster of differentiation (CD) 11a and CD70 promoters in CD4(+ )T ce...

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Detalles Bibliográficos
Autores principales: Zhao, Ming, Wu, Xiaoyan, Zhang, Qing, Luo, Shuangyan, Liang, Gongping, Su, Yuwen, Tan, Yixin, Lu, Qianjin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046540/
https://www.ncbi.nlm.nih.gov/pubmed/21192791
http://dx.doi.org/10.1186/ar3214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046540/
https://www.ncbi.nlm.nih.gov/pubmed/21192791
http://dx.doi.org/10.1186/ar3214

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