Diabetes in Mice With Selective Impairment of Insulin Action in Glut4-Expressing Tissues

OBJECTIVE: Impaired insulin-dependent glucose disposal in muscle and fat is a harbinger of type 2 diabetes, but murine models of selective insulin resistance at these two sites are conspicuous by their failure to cause hyperglycemia. A defining feature of muscle and fat vis-à-vis insulin signaling i...

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Detalles Bibliográficos
Autores principales: Lin, Hua V., Ren, Hongxia, Samuel, Varman T., Lee, Hui-Young, Lu, Taylor Y., Shulman, Gerald I., Accili, Domenico
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046830/
https://www.ncbi.nlm.nih.gov/pubmed/21266328
http://dx.doi.org/10.2337/db10-1056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046830/
https://www.ncbi.nlm.nih.gov/pubmed/21266328
http://dx.doi.org/10.2337/db10-1056

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