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Diabetes in Mice With Selective Impairment of Insulin Action in Glut4-Expressing Tissues

OBJECTIVE: Impaired insulin-dependent glucose disposal in muscle and fat is a harbinger of type 2 diabetes, but murine models of selective insulin resistance at these two sites are conspicuous by their failure to cause hyperglycemia. A defining feature of muscle and fat vis-à-vis insulin signaling i...

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Detalles Bibliográficos
Autores principales:	Lin, Hua V., Ren, Hongxia, Samuel, Varman T., Lee, Hui-Young, Lu, Taylor Y., Shulman, Gerald I., Accili, Domenico
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046830/ https://www.ncbi.nlm.nih.gov/pubmed/21266328 http://dx.doi.org/10.2337/db10-1056

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